Raj Chaklashiya – @RajChaklashiya
Here we present design principles for Dynamic Nuclear Polarization (DNP) utilizing narrow-line Electron Spin Clusters (ESC) to achieve nuclear spin resonance matching (ESC-DNP) for 1H NMR signal enhancement at 7 T, with potential for wide radical design scope at high magnetic field and low microwave power.
Sajith V Sadasivan – @v_sadasivan
Optically activated DNP techniques involving triplet state excitation use non-equilibrium electron spin polarization for room temperature measurements. Despite the advancements in the field, electron spin dynamics during polarization transfer to nuclei remain unexplored. This study aims to understand the electron spin dynamics of a photoexcited triplet system coupled to nuclei.
Ribal Jabbour – @JabbourRibal
Traditional DNP transfer employs an indirect, spin-diffusion mediated process, transferring polarization from nuclei on the PA to solvent nuclei, and then to the target molecule nuclei. In contrast, direct transfer involves immediate polarization from the PA to the target molecule, bypassing any intermediary nuclei. We show the distinctions between indirect and direct transfer methods using AMUPol, a widely-used bis-nitroxide, at magnetic fields ranging from 9 T to 14 T. We demonstrate that with ASYMPol-POK (larger e-e couplings), superior direct transfer performance in deuterated DNP solvent is shown compared to AMUPol.
Natalie Ibbetson – @Natalieeibby
15N-DNP has been proven to work up to only 5 T, while other nuclei (13C, 31P) show enhancements up to 14.1 T. Here we show preliminary experiments conducted at 14.1 T on a solution of 15N-aniline doped with BDPA radical and numerical simulation of electron-nuclear hyperfine coupling.
Shubham Kumar Debadatta – @shubham_k_deb
The study explores enhancing NMR sensitivity using dynamic nuclear polarization with diamond NV-center, aiming to transfer polarization to nearby nuclear spin using NV-electron spin and microwave pulses, avoiding traditional cryogenic methods and costly equipment.
Tomasz Ratajczyk – @TRatajczykonX
Under specific conditions, orthohydrogen generated from parahydrogen can appear to have a partially negative 1H-NMR line (PNL). We present that in some solvents, PNL appears with a positive-negative pattern, while in others, PNL has a negative-positive pattern. The modulation of PNL in a mixture of various solvents will be discussed.
Reza Farsi, Nergiz Sahin Solmaz, Giovanni Boero – @lmis1_epfl @NergizSahin
We report on the design of a single-chip X-band pulsed ESR detector (0.7 mm²), and results of single pulse, Hahn echo, two echoes, Carr-Purcell, and inversion recovery echo measurements at room temperature. We measured 8×10⁷ spins/Hz^(1/2) spin sensitivity on a 0.1 nL sensitive volume, with <100 mW power consumption.
Florin Teleanu – @teleanuflorin
One way to investigate batteries’s health is by analyzing the state of its electrolytes. Here, we develop a computational methodology to predict magnetization lifetimes in multi-spin systems like NaBF4 electrolyte through a combination of molecular and spin dynamics simulations.
Anna Mololina – @Anikkks
Our research addresses the challenges posed by polymorphism in pharmaceuticals, focusing on bicalutamide, a treatment for prostate cancer. Using NOESY spectroscopy and computational methods, we analyzed the spatial structure of bicalutamide in DMSO-d6, providing detailed insights into its conformational behavior.
Shovik Ray – @ray_shovik
Cross-polarization (CP) is an indispensable part of solid-state nuclear magnetic resonance (NMR) spectroscopy to enhance sensitivity and extract structural information. However, the most common CP experiments are susceptible to anisotropic interactions (CSA and QC). A new OC pulse, OPTIANS will be presented which shows 50% better 19F-7Li/23Na PT efficiency compared to ramped CP, both in simulations and experimentally.
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