Triggered functional dynamics of AsLOV2 by time-resolved electron paramagnetic resonance at high magnetic fields

Brad D. Price – @braddprice

My EPR poster submission for #GlobalnmrTC2022. We (@shiny_maity, @songihanlab, @arnab_mukh3rjee, @SpinLovett, and others) are working on filming protein motion in real time using EPR. Initial results on AsLOV2 — a photoactive protein found in plants — are quite promising! pic.twitter.com/MxFcNpUguC

— Brad Price (@braddprice) August 3, 2022

An in-depth functional understanding of proteins requires a technique for tracking their movement in real time. We present high-field, (tr)EPR ‘filming’ of room-temperature protein motion as progress toward real-time distance tracking in lifelike environments.