Hunting evidence of aggregation in ADP and the influence of ion binding

Kelsey Marr – @kelsey_marr

Check out my work on understanding ADP and ionic interactions through NMR! #GlobalnmrTC2023 pic.twitter.com/9QEaTky3gp

— Kelsey Marr (@kelsey_marr) July 19, 2023

Magnesium is the most abundant divalent cation in the cell and essential to nearly every biochemical reaction involving adenosine triphosphate and its lower energy counterpart, adenosine diphosphate. This work has focused on using 31P and 1H NMR as a tool to understand chemical and molecular interactions between ADP and Mg for evidence of nucleotide aggregation either by self-association or influenced by cations.