Events

Title to be announced Abstract to be announced. 8:00 AM California or 11:00 AM Boston or 5:00 PM Paris or 8:30 PM Delhi

Resolving Protein–Ligand Binding Pathways by NMR Relaxation: Conformational Selection vs Induced Fit Protein–ligand binding is essential for biological function. A long-standing question is whether ligand binding occurs via conformational selection (CS) or induced fit (IF). Using relaxation dispersion experiments with varying ligand concentration, we measured the 4-state binding kinetics encompassing both the CS and IF […]

Advancing Magnetic (Resonance) Methods to Track Processes inParamagnetic Battery Electrodes Solid-state NMR has become an indispensable tool for quantifying defects and tracking the nature and reversibility of local structure changes in battery electrode materials during charge and discharge. Yet, probing paramagnetically concentrated systems with NMR remains extremely challenging. Achieving sufficient spectral resolution requires low magnetic […]

Ultra-Wideline Solid-State NMR Spectroscopy with Applications to Battery Materials and (Inter)Metallic Phases This talk will introduce recent advancements in ultra-wideline NMR techniques, focusing on the design principles of WURST pulses for optimal recording of ultra-wideline WCPMG NMR spectra, ultrafast WURST pulses for nuclei with short T2/T2*, and the incorporation of WCPMG under MAS conditions (WCPMG-MAS). […]

Stability of MOFs in the presence of water by solid-state NMR The stability of MOFs in the presence of water is a key factor for their performance in numerous applications. We demonstrated that quadrupolar nuclei like 17O and 91Zr offer unique insight into the inorganic cluster of MOFs such as Zirconium-based UiO-66, despite the low […]

Nuclear and Electron Spins and their Interactions NMR and Electron Paramagnetic Resonance (EPR) share much in common, but the much larger magnetic moment of the electron spin give rise to distinct practical differences given the much higher frequency range accessed in EPR spectroscopy.  I will discuss some methods such as ENDOR and DNP where both […]

Title to be announced Abstract to be announced. 8:00 AM California or 11:00 AM Boston or 5:00 PM Paris or 9:30 PM Delhi

One, two, three… many. What modern pulse EPR knows about nuclei In recent years, understanding the role of nuclear environment in pulse electron paramagnetic resonance (EPR) spectroscopy has been vigorously boosted. In particular, many advances were made in the investigation of nuclear-induced electron spin decoherence kinetics. In this talk, we review these mechanisms, illustrated by […]

In-cell NMR in human cells: from protein maturation to real-time ligand screening In-cell NMR spectroscopy is a unique approach to study protein structure and function in the native cellular environment at atomic resolution. Here I will provide an overview of how NMR analysis of human cells expressing isotope labelled proteins allows monitoring functional processes such […]